Company Profile

Bioactive Bone Substitutes Ltd. (BBS) is a biomedical technology company positioned within the orthopedics market space and focused in the orthobiologics market segment. The company is developing innovative medical device implants for the bone graft substitutes market. Our unique bioactive implants offer financial and clinical benefits in bone healing for hospitals orthopedic surgeons and patients

Growing market, Medical need

The bone grafts market ($2.4 B) is large, stable and growing. A key market driver is an aging population with demand for a high quality musculosceletal function well into old age. Osteoporosis will often lead to joint degeneration which requires surgical repair by fusion. Fusion surgery and hard to hela fractures, are primary needs for bone grafting. Companies competing in this rapidly growing market continue to develop substitutes to patients' own bone transplant, or autograft. These bone graft substitutes spare the patient and surgeon as second surgery which is needed which is needed to harvest bone for grafting, however must match the performance of an autograft.

The current primary bone graft substitute is processed donated human cadaver bone, or allograft. Allografts carry risks of disease transmission and have a weak ability to induce the formation of healthy new bone. This allograft source is severely limited in supply and varies greatly in quality. These are the key market restraints which prevent human bone supply from meeting an ever increasing demand for an optimal bone graft product. .

Our innovative solution

Bioactive Bone Substitutes Ltd. has a unique solution to the medical need. Our first orthobiological product, ARTEBONE®, is made of an unlimited animal source of bone material that has a superior capabilityfor bone regeneration compared to existing allograft products. ARTEBONE® is engineered to consistently deliver a broad spectrum of bone growth factors, and has zero risk of transmitting human disease agents. The source material and proprietary manufacturing process we have developed guarantees a consistent high level of performance.

ARTEBONE® should achieve rapid market acceptance based on the high level associated with its safety, reliability, and exceptional performance. While the initial target market area is orthopedics, there are significant growth opportunities in spinal, oral-craniomaxiollofacial and periodontal/dental applications for this innovative biomaterial.